O6-Methylguanine-DNA-Methyltransferase (MGMT) Peptid
MGMT
Reaktivität: Säugetier
Wirt: Synthetic
BP, WB, IHC
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- Target Alle MGMT Produkte
- MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
- Protein-Typ
- Synthetic
- Spezies
- Säugetier
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- ISYQQLAALA GNPKAARAVG GAMRGNPVPI LIPCHRVVCS SGAVGNYSGG
- Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of MGMT antibody,
Alternative Names: MGMT control peptide, MGMT antibody Blocking Peptide, Anti-MGMT Blocking Peptide, O-6-MethylRNA guanine-Dna Methyltransferase Blocking Peptide - Aufreinigung
- The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
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- Applikationshinweise
- Optimal conditions should be determined by the investigator
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C long term.
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- Target
- MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
- Synonyme
- AGT Peptide, AI267024 Peptide, Agat Peptide, O-6-methylguanine-DNA methyltransferase Peptide, MGMT Peptide, Mgmt Peptide
- Hintergrund
- MGMT is involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA.MGMT repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
- Molekulargewicht
- 22 kDa
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