G-Elongation Factor, Mitochondrial 1 (GFM1) (Middle Region) Peptid
GFM1
Reaktivität: Human, Maus
Wirt: Synthetic
BP, WB
Produktnummer ABIN977370
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 15 bis 22 Werktagen
Kurzübersicht für G-Elongation Factor, Mitochondrial 1 (GFM1) (Middle Region) Peptid (ABIN977370)
Target
GFM1
(G-Elongation Factor, Mitochondrial 1 (GFM1))
Spezies
Human, Maus
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- ISIAMRPSNK NDLEKFSKGI GRFTREDPTF KVHFDPESKE TIVSGMGELH
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-Gfm1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GFM1 (G-Elongation Factor, Mitochondrial 1 (GFM1))
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Hintergrund
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Gfm1 is a mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Gfm1 catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Gfm1 does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.
Alias Symbols: AW545374, D3Wsu133e, Gfm
Protein Size: 751 -
Molekulargewicht
- 83 kDa
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Gen-ID
- 28030
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NCBI Accession
- NM_138591, NP_613057
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UniProt
- Q8K0D5
Target
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