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G-Elongation Factor, Mitochondrial 1 (GFM1) (C-Term) Peptid

GFM1 Reaktivität: Human, Maus Wirt: Synthetic BP, WB
Produktnummer ABIN977369
  • Target Alle GFM1 Produkte
    GFM1 (G-Elongation Factor, Mitochondrial 1 (GFM1))
    Protein Region
    C-Term
    Spezies
    Human, Maus
    Quelle
    • 2
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    ELRSCTEGKG EYTMEYCRYQ PCSPSTQEEL INKYLEATGQ LPVKKGKAKN
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-Gfm1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    GFM1 (G-Elongation Factor, Mitochondrial 1 (GFM1))
    Synonyme
    COXPD1 Peptide, EFG Peptide, EFG1 Peptide, EFGM Peptide, EGF1 Peptide, GFM Peptide, hEFG1 Peptide, AW545374 Peptide, D3Wsu133e Peptide, Gfm Peptide, EF-G Peptide, Efg Peptide, G elongation factor mitochondrial 1 Peptide, G elongation factor, mitochondrial 1 Peptide, GFM1 Peptide, Gfm1 Peptide
    Hintergrund
    Gfm1 is a mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Gfm1 catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Gfm1 does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.

    Alias Symbols: AW545374, D3Wsu133e, Gfm

    Protein Size: 751
    Molekulargewicht
    83 kDa
    Gen-ID
    28030
    NCBI Accession
    NM_138591, NP_613057
    UniProt
    Q8K0D5
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