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F-Box and Leucine-Rich Repeat Protein 3 (FBXL3) (C-Term) Peptid

FBXL3 Reaktivität: Human, Maus Wirt: Synthetic BP, WB
Produktnummer ABIN976718

Kurzübersicht für F-Box and Leucine-Rich Repeat Protein 3 (FBXL3) (C-Term) Peptid (ABIN976718)

Target

FBXL3 (F-Box and Leucine-Rich Repeat Protein 3 (FBXL3))

Spezies

Human, Maus

Quelle

  • 4
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequenz

    ELLLALSSEK HVRLEHLRID VVSENPGQTH FHTIQKSSWD AFIKHSPKVN

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-Fbxl3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    FBXL3 (F-Box and Leucine-Rich Repeat Protein 3 (FBXL3))

    Hintergrund

    Fbxl3 is a substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex involved in circadian clock function. The SCF(FBXL3) complex acts by mediating ubiquitination and subsequent degradation of CRY1 and CRY2. Recruiter of target protein that may recognize and bind to some phosphorylated proteins and promotes their ubiquitination and degradation.

    Alias Symbols: AU041772, AW212966, FBK, Fbl3a, Fbxl3a, Ovtm

    Protein Size: 428

    Molekulargewicht

    49 kDa

    Gen-ID

    50789

    NCBI Accession

    NM_015822, NP_056637

    UniProt

    Q8C4V4
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