Estrogen Receptor 1 (ESR1) (Middle Region) Peptid
ESR1
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle Estrogen Receptor alpha (ESR1) Produkte
- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
- Protein Region
- Middle Region
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-ESR1 antibody (Catalog #: P100873_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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-
- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
- Hintergrund
-
ESR1 is an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.
Alias Symbols: DKFZp686N23123, ER, ESR, ESRA, Era, NR3A1
Protein Interaction Partner: ANP32A,AXIN2,BCAS2,BLOC1S1,CCND1,CHUK,CTNNB1,DDX17,DDX5,EBAG9,EIF3I,EP300,ESR2,HDAC1,JUN,JUNB,KDM5A,MED1,MPG,MYC,NCOA1,NCOA2,NCOA3,NCOA3,NCOR1,NCOR2,NRIP1,PGR,PGR,PHB2,PRMT2,RBM23,STAT5A,TFF1,TFF1,TP53,TRIM24,TRRAP,AP1B1,ASCC2,BAGE3,C21orf129,CELSR1,CSNK1E,CYB5R3,DSCAM,FHL2,LOC441967,NCAM2,NRIP1,PIAS1,SFI1,SLC37A1,SNAP29,SOD1,TFF1,TFF1,THOC5,UBE2I,XBP1,AHR,AKAP13,AKT1,AKT2,AR,ARHGEF15,ARNT,BAG1,BCAR1,BCAS2,BDNF,BRCA1,CALM1,CALM3,CALM3,CAV1,CCND1,CCNH,CCNT1,CDC25B,CDK7,CEBPB,CHD9,CHUK,CITED1,COBRA1,COPS5,CREBBP,CSNK2B,CTNNB1,CUEDC2,CUL4B,DDX5,DDX54,DNTTIP2,DUT,EGFR,EIF3I,EP300,ERBB2,ESR1,ESR2,ESRRA,FHL2,FLII,FOXO1,FOXO3,FOXO4,GADD45B,GADD45G,GNAI1,GRB2,GTF2B,GTF2H1,HEXIM1,HNF4A,HSP90AA1,HSP90AB1,HSPA4,IGF1R,ISL1,ITGB3BP,JUN,JUNB,JUND,KAT5,KDM5A,KIF1A,LCK,LOH3CR2A,MAPK1,MAPK14,MAPK3,MDM2,MED1,MED24,MKNK2,MLL2,MMS19,MNAT1,MPG,MTA1,MTCH2,MVP,NCOA1,NCOA2,NCOA3,NCOA6,NCOA7,NCOR1,NCOR2,NFKB1,NPPA,NR0B1,NR0B2,NR1H4,NR2C1,NR2C2,NR2F1,NR2F6,NRIP1,NSD1,PAK1,PAK6,PELP1,PGR,PHB2,PIAS1,PIAS3,PIK3R1,PIK3R3,PNRC2,POLR1B,POLR2D,POU2F1,POU4F1,POU4F2,PPARGC1A,PPARGC1B,PRDM2,PRKACA,PRMT1,PRMT2,PSMC5,PTGES3,PTPN1,PTPN6,RARA,RBM23,RBM39,RBM9,RELA,REXO4,RFX4,RGS3,RNF14,RNF4,RPS6KA1,RPS6KA3,RXRA,SAFB,SAFB2,SHC1,SLC30A9,SMAD2,SMAD3,SMAD4,SMARCA2,SMARCA4,SMARCD3,SMARCE1,SOS1,SP1,SP3,SRC,SREBF1,STAT5A,STRN,STUB1,TAF10,TAP1,TBP,TCF20,TDG,THRA,THRB,TNFRSF14,TP53,TRIM24,TRIM28,TRIM59,TRIP4,TRRAP,TSC2,TUBA1B,TUBB,UBE2I,USF1,WIPI1,XBP1,YWHAH,ZBTB16,ZBTB17,ZNF398,AHR,AKAP13,BAG1,BAZ1B,BRCA1,CAV1,CCNC,CCND1,CCNH,CDC25B,CDK7,CDK8,CEBPA,CEBPB,COBRA1,CREBBP,CTNNB1,DAP3,DDX17,DDX5,DDX54,DNTTIP2,EP300,ESR1,ESR2,FKBP4,FKBP5,FOXO1,FOXO4,GADD45A,GADD45G,GTF2H1,Gadd45b,HSP90AA1,HSPA4,IGF1R,ISL1,JUN,KAT5,KDM5A,LDB1,MAPK1,MDM2,MED1,MED10,MED12,MED13,MED14,MED16,MED17,MED20,MED21,MED23,MED24,MED6,MED7,MGMT,MNAT1,MTA1,MVP,NCOA1,NCOA2,NCOA3,NCOA4,NCOA6,NCOA7,NCOR1,NGG1,NR0B2,NR2C1,NR2C2,NR2F1,NR2F6,NRIP1,Nr0b2,Nr1i2,Nsd1,PAK6,PDLIM1,PELP1,PHB2,PIAS2,PIK3R1,POU2F1,POU2F2,POU4F1,POU4F2,PPARGC1A,PPARGC1B,PPID,PRDM2,PRMT1,PRMT2,PTEN,PTGES3,PTMA,RBM39,RBM9,REXO4,RLIM,RNF4,SAFB,SAFB2,SHC1,SMAD2,SMARCA2,SMARCA4,SMARCD1,SMARCE1,SRA1,SRC,STAT3,STAT5A,SVIL,TADA3,TBP,TDG,TP53,TRAM1,TRIM24,TRIM25,TRIP4,TRRAP,Tada3,UBC,XBP1,YWHAQ,ZBTB16,ZNF398
Protein Size: 595 - Molekulargewicht
- 66 kDa
- Gen-ID
- 2099
- NCBI Accession
- NM_000125, NP_000116
- UniProt
- P03372
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