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Erythropoietin Receptor (EPOR) (N-Term) Peptid

EPOR Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN976391
  • Target Alle EPOR Produkte
    EPOR (Erythropoietin Receptor (EPOR))
    Protein Region
    N-Term
    Spezies
    Human
    Quelle
    • 4
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-EPOR antibody (Catalog #: ARP44216_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    EPOR (Erythropoietin Receptor (EPOR))
    Synonyme
    EPOR Peptide, epor Peptide, EPO-R Peptide, erythropoietin receptor Peptide, erythropoietin receptor L homeolog Peptide, EPOR Peptide, epor Peptide, Epor Peptide, epor.L Peptide
    Hintergrund
    The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis.The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: MGC138358, EPO-R

    Protein Interaction Partner: EPO,EPO,EPOR,GNB2L1,ATXN2L,CBL,CISH,CRKL,CSF2RB,EPO,EPOR,GAB1,GAB2,GNAI1,GNB2L1,GRAP,GRB2,INPP5D,IRS2,JAK2,KIT,KITLG,KLK3,LYN,MAPK1,MAPK3,MST1R,PIK3R1,PLCG1,PLCG2,PTPN11,PTPN6,SH2B2,SHC1,SOCS2,SOCS3,STAT5A,STAT5B,SYK,VAV1,ATXN2L,BTRC,CISH,CRKL,EPO,GNAI1,GNB2L1,GRAP,GRB2,IRS2,JAK2,LYN,PIK3R1,PTPN11,PTPN6,SHC1,SOCS2,SOCS3,STAT5A,SYK,SYP,VAV1

    Protein Size: 508
    Molekulargewicht
    53 kDa
    Gen-ID
    2057
    NCBI Accession
    NM_000121, NP_000112
    UniProt
    P19235
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