Erythropoietin Receptor (EPOR) Peptid
Kurzübersicht für Erythropoietin Receptor (EPOR) Peptid (ABIN937364)
Target
Spezies
Quelle
Applikation
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Protein-Typ
- Synthetic
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Sequenz
- DHLGASLWPQ VGSLCLLLAG AAWAPPPNLP DPKFESKAAL LAARGPEELL
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of EPOR antibody,
Alternative Names: EPOr control peptide, EPOr antibody Blocking Peptide, Anti-EPOr Blocking Peptide, Erythropoietin Receptor Blocking Peptide, MGC138358 Blocking Peptide -
Aufreinigung
- Prepared from rabbit serum by affinity purification via sequential chromatography on phospho- and dephosphopeptide affinity columns.
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- EPOR (Erythropoietin Receptor (EPOR))
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Hintergrund
- The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis.
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Molekulargewicht
- 53 kDa
Target
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