Dickkopf 2 Homolog (DKK2) (Middle Region) Peptid
DKK2
Reaktivität: Maus
Wirt: Synthetic
BP, WB
-
- Target Alle DKK2 Produkte
- DKK2 (Dickkopf 2 Homolog (DKK2))
- Protein Region
- Middle Region
- Spezies
- Maus
-
Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- NGICIPVTES ILTPHIPALD GTRHRDRNHG HYSNHDLGWQ NLGRPHSKMP
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-Dkk2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
-
Dickkopf 2 Homolog (DKK2) peptide
DKK2 Reaktivität: Human, Maus, Rind (Kuh), Hund, Ratte Wirt: Synthetic BP, Imm
-
- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- DKK2 (Dickkopf 2 Homolog (DKK2))
- Hintergrund
-
Dkk2 antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer's disease.
Alias Symbols: -
Protein Size: 259 - Molekulargewicht
- 28 kDa
- Gen-ID
- 56811
- NCBI Accession
- NM_020265, NP_064661
- UniProt
- Q9QYZ8
-
Sie sind hier:
