Chemokine (C-X-C Motif) Receptor 4 (CXCR4) Peptid
CXCR4
Reaktivität: Human
Wirt: Synthetic
BP, WB, IHC, FACS
Produktnummer ABIN975479
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 15 bis 22 Werktagen
Kurzübersicht für Chemokine (C-X-C Motif) Receptor 4 (CXCR4) Peptid (ABIN975479)
Target
CXCR4
(Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-CXCR4 antibody (Catalog #: ARP30799_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Chemokine (C-X-C Motif) Receptor 4 (CXCR4) peptide
CXCR4 Wirt: Synthetic BP, WB, IHC
Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 26-37) peptide (Ovalbumin)CXCR4 Reaktivität: Human Wirt: Synthetic WB, Imm, SDS
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
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Hintergrund
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CXCR4 is a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM
Protein Interaction Partner: CXCL12,ADRBK2,ARRB2,CCR5,CD4,CTSG,CXCL12,CXCR4,DPP4,ELANE,GNA13,GNAI1,HSPA8,JAK1,JAK2,JAK3,MYH9,PTK2,PTPN11,PTPN6,PTPRC,SDC4,SOCS1,SOCS3,STAT1,STAT2,STAT3,STAT5B,VAV1,ADRBK2,CCR5,CD4,ITCH,JAK2,JAK3,PTK2,PTPN6,SOCS3,UBC,USP14
Protein Size: 352 -
Molekulargewicht
- 40 kDa
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Gen-ID
- 7852
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NCBI Accession
- NM_003467, NP_003458
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UniProt
- P61073
Target
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