Chemokine (C-X-C Motif) Receptor 4 (CXCR4) Peptid
Kurzübersicht für Chemokine (C-X-C Motif) Receptor 4 (CXCR4) Peptid (ABIN8096876)
Target
Quelle
Applikation
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Verwendungszweck
- CXCR4 Peptide
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Chemokine (C-X-C Motif) Receptor 4 (CXCR4) peptide
CXCR4 Wirt: Synthetic BP, WB, IHC
Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 26-37) peptide (Ovalbumin)CXCR4 Reaktivität: Human Wirt: Synthetic WB, Imm, SDS
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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This is a synthetic peptide designed for use in combination with anti-CXCR4 antibody ( ARP30799_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
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Hintergrund
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Background Information: CXCR4 is a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alternative Symbols: CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM
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Molekulargewicht
- 40kDa
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Gen-ID
- 7852
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NCBI Accession
- NP_003458
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UniProt
- P61073
Target
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