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CAMP Responsive Element Modulator (CREM) Peptid

CREM Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN975303
  • Target Alle CREM Produkte
    CREM (CAMP Responsive Element Modulator (CREM))
    Spezies
    Human
    Quelle
    • 6
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-CREM antibody (Catalog #: ARP34777_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    CREM (CAMP Responsive Element Modulator (CREM))
    Synonyme
    CREM Peptide, ICER Peptide, CREM-2 Peptide, hCREM-2 Peptide, ICERI Peptide, Icer Peptide, cAMP responsive element modulator Peptide, CREM Peptide, Crem Peptide
    Hintergrund
    CREM is a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription.

    Alias Symbols: ICER, CREM-2, hCREM-2

    Protein Interaction Partner: CDC34,CREB1,FHL5,KCNIP3,SPI1,TAF4,TBP,ATF1,CAMK2D,CAMK2G,CDC34,CDK1,CREB1,CREB3L1,CREBBP,CREM,CSNK1A1,CSNK2A1,CSNK2A2,FHL5,GSK3A,GSK3B,KCNIP3,PRKACA,PRKCA,SPI1,TAF4,TBP,CD34,FHL5,KCNIP3,SPI1,TAF4,TBP

    Protein Size: 120
    Molekulargewicht
    13 kDa
    Gen-ID
    1390
    NCBI Accession
    NM_182717, NP_874386
    UniProt
    O75519
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