CAMP Responsive Element Modulator (CREM) (C-Term) Peptid
CREM
Reaktivität: Human, Ratte
Wirt: Synthetic
BP, WB
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- Target Alle CREM Produkte
- CREM (CAMP Responsive Element Modulator (CREM))
- Protein Region
- C-Term
- Spezies
- Human, Ratte
-
Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- KNREAARECR RKKKEYVKCL ENRVAVLENQ NKTLIEELKA LKDLYCHKAE
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-Crem Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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CAMP Responsive Element Modulator (CREM) peptide
CREM Reaktivität: Human, Ratte, Rind (Kuh), Maus Wirt: Synthetic BP, Imm
-
- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- CREM (CAMP Responsive Element Modulator (CREM))
- Synonyme
- CREM Peptide, ICER Peptide, CREM-2 Peptide, hCREM-2 Peptide, ICERI Peptide, Icer Peptide, cAMP responsive element modulator Peptide, CREM Peptide, Crem Peptide
- Hintergrund
-
Crem is a transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Isoform Delta is an activator. Crem plays a role in spermatogenesis and is involved in spermatid maturation. Binding of isoform Tau (activator) to CRE is increased by CREB3L4. The CREM isoform Tau-CREB3L4 heterodimer functions through CRE and may recruit HIRA to CRE to regulate histone exchange.
Alias Symbols: Icer
Protein Size: 357 - Molekulargewicht
- 39 kDa
- Gen-ID
- 25620
- NCBI Accession
- NM_001110860, NP_001104330
- UniProt
- Q03061
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