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CAMP Responsive Element Modulator (CREM) Peptid

CREM Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN975303

Kurzübersicht für CAMP Responsive Element Modulator (CREM) Peptid (ABIN975303)

Target

CREM (CAMP Responsive Element Modulator (CREM))

Spezies

Human

Quelle

  • 6
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-CREM antibody (Catalog #: ARP34777_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    CREM (CAMP Responsive Element Modulator (CREM))

    Hintergrund

    CREM is a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription.

    Alias Symbols: ICER, CREM-2, hCREM-2

    Protein Interaction Partner: CDC34,CREB1,FHL5,KCNIP3,SPI1,TAF4,TBP,ATF1,CAMK2D,CAMK2G,CDC34,CDK1,CREB1,CREB3L1,CREBBP,CREM,CSNK1A1,CSNK2A1,CSNK2A2,FHL5,GSK3A,GSK3B,KCNIP3,PRKACA,PRKCA,SPI1,TAF4,TBP,CD34,FHL5,KCNIP3,SPI1,TAF4,TBP

    Protein Size: 120

    Molekulargewicht

    13 kDa

    Gen-ID

    1390

    NCBI Accession

    NM_182717, NP_874386

    UniProt

    O75519
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