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CD27 Molecule (CD27) (C-Term) Peptid

CD27 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN974660
  • Target Alle CD27 Produkte
    CD27 (CD27 Molecule (CD27))
    Protein Region
    C-Term
    Spezies
    Human
    Quelle
    • 3
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    LHQRRKYRSN KGESPVEPAE PCRYSCPREE EGSTIPIQED YRKPEPACSP
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-CD27 Antibody(ARP59093_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    CD27 (CD27 Molecule (CD27))
    Hintergrund
    The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

    Alias Symbols: MGC20393, S152, T14, TNFRSF7, Tp55

    Protein Interaction Partner: CD70,SIVA1,TRAF2,TRAF3,TRAF5,CD5,SIVA1,TRAF1,TRAF2,TRAF3,TRAF5

    Protein Size: 260
    Molekulargewicht
    27 kDa
    Gen-ID
    939
    NCBI Accession
    NM_001242, NP_001233
    UniProt
    P26842
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