CD27 Molecule (CD27) (C-Term) Peptid
CD27
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle CD27 Produkte
- CD27 (CD27 Molecule (CD27))
- Protein Region
- C-Term
- Spezies
- Human
-
Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- LHQRRKYRSN KGESPVEPAE PCRYSCPREE EGSTIPIQED YRKPEPACSP
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-CD27 Antibody(ARP59093_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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-
- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- CD27 (CD27 Molecule (CD27))
- Hintergrund
-
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Alias Symbols: MGC20393, S152, T14, TNFRSF7, Tp55
Protein Interaction Partner: CD70,SIVA1,TRAF2,TRAF3,TRAF5,CD5,SIVA1,TRAF1,TRAF2,TRAF3,TRAF5
Protein Size: 260 - Molekulargewicht
- 27 kDa
- Gen-ID
- 939
- NCBI Accession
- NM_001242, NP_001233
- UniProt
- P26842
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