A synthetic peptide for use as a blocking control in assays to test for specificity of CD27 antibody, Alternative Names: CD27 control peptide, CD27 antibody Blocking Peptide, Anti-CD27 Blocking Peptide, CD27 molecule Blocking Peptide, MGC20393 Blocking Peptide, S152 Blocking Peptide, T14 Blocking Peptide, TNFRSF7 Blocking Peptide, Tp55 Blocking Peptide, CD27, CD-27, CD 27, CD-27 Blocking Peptide, CD 27 Blocking Peptide
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.