Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4) Peptid
CACNB4
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN974380
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 15 bis 22 Werktagen
Kurzübersicht für Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4) Peptid (ABIN974380)
Target
CACNB4
(Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-CACNB4 antibody (Catalog #: ARP34959_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CACNB4 (Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))
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Hintergrund
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CACNB4 is a member of the beta subunit family, a protein in the voltage-dependent calcium channel complex. CACNB4 plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. This gene encodes a member of the beta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein described in this record plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME). Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized.
Alias Symbols: CAB4, CACNLB4, EA5, EJM, EIG9, EJM4, EJM6
Protein Interaction Partner: CACNA1A,MED31,PTN,REM1,TBL3,CACNA1A,MED31,PTN,TBL3
Protein Size: 486 -
Molekulargewicht
- 55 kDa
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Gen-ID
- 785
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NCBI Accession
- NM_001005747, NP_001005747
Target
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