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Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4) Peptid

CACNB4 Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN939035
  • Target Alle CACNB4 Produkte
    CACNB4 (Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))
    Protein-Typ
    Synthetic
    Spezies
    Säugetier
    Quelle
    • 6
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    GVPDPGTGAS SGTRTPDVKA FLESPWSLDP ASASPEPVPH ILASSRQWDP
    Produktmerkmale
    A synthetic peptide for use as a blocking control in assays to test for specificity of CACNB4 antibody,
    Alternative Names: CACNB4 control peptide, CACNB4 antibody Blocking Peptide, Anti-CACNB4 Blocking Peptide, Calcium Channel Voltage-Dependent Beta 4 Subunit Blocking Peptide, CACNB4, CACNB-4, CACNB 4, CACNB-4 Blocking Peptide, CACNB 4 Blocking Peptide
  • Applikationshinweise
    Optimal conditions should be determined by the investigator
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C long term.
  • Target
    CACNB4 (Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))
    Synonyme
    CAB4 Peptide, CACNLB4 Peptide, EA5 Peptide, EIG9 Peptide, EJM Peptide, EJM4 Peptide, EJM6 Peptide, 3110038O15Rik Peptide, Cchb4 Peptide, lethargic Peptide, lh Peptide, CACNB4 Peptide, cacnb4.2 Peptide, calcium voltage-gated channel auxiliary subunit beta 4 Peptide, calcium channel, voltage-dependent, beta 4 subunit Peptide, calcium channel, voltage-dependent, beta 4a subunit Peptide, CACNB4 Peptide, Cacnb4 Peptide, cacnb4.1 Peptide, cacnb4 Peptide, cacnb4a Peptide
    Hintergrund
    CACNB4 is a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. CACNB4 plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME).
    Molekulargewicht
    50 kDa
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