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Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4) Peptid

CACNB4 Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN939035
382,12 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 20 bis 27 Werktagen

Kurzübersicht für Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4) Peptid (ABIN939035)

Target

CACNB4 (Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))

Spezies

Säugetier

Quelle

  • 5
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Protein-Typ

    Synthetic

    Sequenz

    GVPDPGTGAS SGTRTPDVKA FLESPWSLDP ASASPEPVPH ILASSRQWDP

    Produktmerkmale

    A synthetic peptide for use as a blocking control in assays to test for specificity of CACNB4 antibody,
    Alternative Names: CACNB4 control peptide, CACNB4 antibody Blocking Peptide, Anti-CACNB4 Blocking Peptide, Calcium Channel Voltage-Dependent Beta 4 Subunit Blocking Peptide, CACNB4, CACNB-4, CACNB 4, CACNB-4 Blocking Peptide, CACNB 4 Blocking Peptide
  • Applikationshinweise

    Optimal conditions should be determined by the investigator

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20 °C long term.
  • Target

    CACNB4 (Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))

    Hintergrund

    CACNB4 is a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. CACNB4 plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME).

    Molekulargewicht

    50 kDa
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