alpha-Methylacyl-CoA Racemase (AMACR) (C-Term) Peptid
AMACR
Reaktivität: Human
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN973162
Kurzübersicht für alpha-Methylacyl-CoA Racemase (AMACR) (C-Term) Peptid (ABIN973162)
Target
AMACR
(alpha-Methylacyl-CoA Racemase (AMACR))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein Region
- C-Term
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Sequenz
- IFDGTDACVT PVLTFEEVVH HDHNKERGSF ITSEEQDVSP RPAPLLLNTP
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-AMACR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
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Hintergrund
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This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.
Alias Symbols: CBAS4, RACE, RM, AMACRD
Protein Size: 382 -
Molekulargewicht
- 42 kDa
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Gen-ID
- 23600
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NCBI Accession
- NM_014324, NP_055139
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UniProt
- Q9UHK6
Target
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