A synthetic peptide for use as a blocking control in assays to test for specificity of AMACR antibody, Alternative Names: AMACR control peptide, AMACR antibody Blocking Peptide, Anti-AMACR Blocking Peptide, alpha-methylacyl-CoA racemase Blocking Peptide, CBAS4 Blocking Peptide, RACE Blocking Peptide, RM Blocking Peptide
AMACR
Reaktivität: Human, Ratte
Wirt: Synthetic
BP, WB, ICo, IDe
Applikationshinweise
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
AMACR
(alpha-Methylacyl-CoA Racemase (AMACR))
Hintergrund
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.