Toll-Like Receptor 4 (TLR4) Peptid
TLR4
Reaktivität: Säugetier
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN940355
Kurzübersicht für Toll-Like Receptor 4 (TLR4) Peptid (ABIN940355)
Target
TLR4
(Toll-Like Receptor 4 (TLR4))
Spezies
Säugetier
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein-Typ
- Synthetic
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Sequenz
- LGEFRNEGNL EKFDKSALEG LCNLTIEEFR LAYLDYYLDD IIDLFNCLTN
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of TLR4 antibody,
Alternative Names: TLR4 control peptide, TLR4 antibody Blocking Peptide, Anti-TLR4 Blocking Peptide, toll-like receptor 4 Blocking Peptide, ARMD10 Blocking Peptide, CD284 Blocking Peptide, TOLL Blocking Peptide, hToll Blocking Peptide, TLR4, TLR-4, TLR 4, TLR-4 Blocking Peptide, TLR 4 Blocking Peptide
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Toll-Like Receptor 4 (TLR4) (AA 420-435) peptide (Ovalbumin)
TLR4 Reaktivität: Human Wirt: Synthetic WB, Imm, SDS
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- TLR4 (Toll-Like Receptor 4 (TLR4))
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Hintergrund
- The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes. It has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Also, several transcript variants of this gene have been found, but the protein coding potential of most of them is uncertain.
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Molekulargewicht
- 93 kDa
Target
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