A synthetic peptide for use as a blocking control in assays to test for specificity of TLR8 antibody, Alternative Names: TLR8 control peptide, TLR8 antibody Blocking Peptide, Anti-TLR8 Blocking Peptide, toll-like receptor 8 Blocking Peptide, CD288 Blocking Peptide, MGC119599 Blocking Peptide, MGC119600 Blocking Peptide, TLR8, TLR-8, TLR 8, TLR-8 Blocking Peptide, TLR 8 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
TLR8
(Toll-Like Receptor 8 (TLR8))
Hintergrund
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.