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Toll-Like Receptor 8 (TLR8) (C-Term) Peptid

TLR8 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN985141
  • Target Alle TLR8 Produkte
    TLR8 (Toll-Like Receptor 8 (TLR8))
    Protein Region
    C-Term
    Spezies
    Human
    Quelle
    • 1
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    LEPVLQHSQY LRLRQRICKS SILQWPDNPK AEGLFWQTLR NVVLTENDSR
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-TLR8 Antibody(ARP59048_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    TLR8 (Toll-Like Receptor 8 (TLR8))
    Synonyme
    CD288 Peptide, toll like receptor 8 Peptide, toll-like receptor 8 Peptide, TLR8 Peptide, Tlr8 Peptide
    Hintergrund
    The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.

    Alias Symbols: CD288, MGC119599, MGC119600

    Protein Interaction Partner: BTK,MYD88

    Protein Size: 1041
    Molekulargewicht
    120 kDa
    Gen-ID
    51311
    NCBI Accession
    NM_138636, NP_619542
    UniProt
    Q9NR97
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