A synthetic peptide for use as a blocking control in assays to test for specificity of PHB2 antibody, Alternative Names: Prohibitin 2 control peptide, Prohibitin 2 antibody Blocking Peptide, Anti-Prohibitin 2 Blocking Peptide, BAP Blocking Peptide, BCAP37 Blocking Peptide, Bap37 Blocking Peptide, MGC117268 Blocking Peptide, PNAS-141 Blocking Peptide, REA Blocking Peptide, p22 Blocking Peptide, PHB2 Blocking Peptide
PHB2
Reaktivität: Human, Maus
Wirt: Synthetic
BP, WB, IP
Applikationshinweise
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
Prohibitin 2 (PHB2)
Hintergrund
PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). It functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. PHB2 competes with NCOA1 for modulation of ER transcriptional activity. It probably involved in regulating mitochondrial respiration activity and in aging.