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Prohibitin 2 (PHB2) Peptid

PHB2 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN981665
  • Target Alle Prohibitin 2 (PHB2) Produkte
    Prohibitin 2 (PHB2)
    Spezies
    Human
    Quelle
    • 4
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-PHB2 antibody (Catalog #: ARP48315_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Prohibitin 2 (PHB2)
    Synonyme
    bcap37 Peptide, zgc:73150 Peptide, wu:fc28c08 Peptide, PHB2 Peptide, phb2 Peptide, ATPHB2 Peptide, F21M11.21 Peptide, F21M11_21 Peptide, prohibitin 2 Peptide, DKFZp469N1310 Peptide, BAP Peptide, BCAP37 Peptide, Bap37 Peptide, PNAS-141 Peptide, REA Peptide, p22 Peptide, bap37 Peptide, prohibitin2 Peptide, xphb2 Peptide, AU044498 Peptide, Bcap37 Peptide, Bap Peptide, Bap-37 Peptide, Bcap27 Peptide, prohibitin 2a Peptide, prohibitin 2 Peptide, prohibitin 2 S homeolog Peptide, phb2a Peptide, PHB2 Peptide, phb2 Peptide, phb2.S Peptide, Phb2 Peptide
    Hintergrund
    PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). It functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. PHB2 competes with NCOA1 for modulation of ER transcriptional activity. It probably involved in regulating mitochondrial respiration activity and in aging.

    Alias Symbols: BAP, BCAP37, Bap37, MGC117268, PNAS-141, REA, p22

    Protein Interaction Partner: ESR1,PTMA,AKT1,ESR1,HDAC1,HDAC2,HDAC3,HDAC5,MEF2A,MYOD1,PTMA,UPF2,CDC25B,COPG,CTNNB1,DDX20,EPPK1,ESR1,JUP,LGALS3BP,MMS19,NUP205,NUP93,PDXDC1,PTMA,RIPK2,RUNX3,SERINC3,SIRT2,TFE3,TH1L,TIMM50,USP15

    Protein Size: 299
    Molekulargewicht
    33 kDa
    Gen-ID
    11331
    NCBI Accession
    NM_007273, NP_009204
    UniProt
    Q99623
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