Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3) Peptid
KCNN3
Reaktivität: Säugetier
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN939558
Kurzübersicht für Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3) Peptid (ABIN939558)
Target
KCNN3
(Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3))
Spezies
Säugetier
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein-Typ
- Synthetic
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Sequenz
- ITELNDRSED LEKQIGSLES KLEHLTASFN SLPLLIADTL RQQQQQLLSA
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of KCNN3 antibody,
Alternative Names: KCNN3 control peptide, KCNN3 antibody Blocking Peptide, Anti-KCNN3 Blocking Peptide, Potassium Intermediate/Small Conductance Calcium-Activated Channel Subfamily N Member 3 Blocking Peptide, KCNN3, KCNN-3, KCNN 3, KCNN-3 Blocking Peptide, KCNN 3 Blocking Peptide
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- KCNN3 (Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3))
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Hintergrund
- Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. KCNN3, a member of the KCNN family of potassium channel genes, encodes a protein that is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits.
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Molekulargewicht
- 81 kDa
Target
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