Recombination Activating Gene 1 (RAG1) Peptid
RAG1
Reaktivität: Säugetier
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN939380
Kurzübersicht für Recombination Activating Gene 1 (RAG1) Peptid (ABIN939380)
Target
RAG1
(Recombination Activating Gene 1 (RAG1))
Spezies
Säugetier
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein-Typ
- Synthetic
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Sequenz
- IIERDGSIGA WASEGNESGN KLFRRFRKMN ARQSKCYEME DVLKHHWLYT
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of Rag1 antibody,
Alternative Names: Rag1 control peptide, Rag1 antibody Blocking Peptide, Anti-Rag1 Blocking Peptide, recombination activating gene 1 Blocking Peptide, Rag-1 Blocking Peptide, Rag1, Rag-1, Rag 1, Rag-1 Blocking Peptide, Rag 1 Blocking Peptide
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- RAG1 (Recombination Activating Gene 1 (RAG1))
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Hintergrund
- As a catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities.
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Molekulargewicht
- 119 kDa
Target
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