Recombination Activating Gene 1 (RAG1) (C-Term) Peptid
RAG1
Reaktivität: Maus
Wirt: Synthetic
BP, WB
Produktnummer ABIN982623
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 15 bis 22 Werktagen
Kurzübersicht für Recombination Activating Gene 1 (RAG1) (C-Term) Peptid (ABIN982623)
Target
RAG1
(Recombination Activating Gene 1 (RAG1))
Spezies
Maus
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- C-Term
-
Sequenz
- IIERDGSIGA WASEGNESGN KLFRRFRKMN ARQSKCYEME DVLKHHWLYT
-
Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-Rag1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Aufreinigung
- Purified
-
-
-
-
Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Konzentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handhabung
- Avoid repeated freeze-thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- RAG1 (Recombination Activating Gene 1 (RAG1))
-
Hintergrund
-
As a catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities.
Alias Symbols: Rag-1
Protein Interaction Partner: Nfkb1,Rel,Rela
Protein Size: 1040 -
Molekulargewicht
- 119 kDa
-
Gen-ID
- 19373
-
NCBI Accession
- NM_009019, NP_033045
-
UniProt
- P15919
Target
-
Sie sind hier:
