A synthetic peptide for use as a blocking control in assays to test for specificity of TAF9 antibody, Alternative Names: TAF9 control peptide, TAF9 antibody Blocking Peptide, Anti-TAF9 Blocking Peptide, TAF9 RNA polymerase II, TATA box binding protein, TBP-associated factor, 32kDa Blocking Peptide, TAF9, TAF-9, TAF 9, TAF-9 Blocking Peptide, TAF 9 Blocking Peptide
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation.