RNA Polymerase II TBP-Associated Factor Subunit G (TAF9) Peptid

This is a synthetic peptide designed for use in combination with anti-TAF9 antibody ( ARP34551_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.

Background Information: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds to the basal transcription factor GTF2B as well as to several transcriptional activators such as p53 and VP16.

Alternative Symbols: AK6, CIP, CINAP, TAF2G, AD-004, hCINAP, CGI-137, TAFII31, TAFII32, MGC:1603, MGC:3647, MGC:5067, TAFIID32