A synthetic peptide for use as a blocking control in assays to test for specificity of UBE2 K antibody, Alternative Names: UBE2K control peptide, UBE2K antibody Blocking Peptide, Anti-UBE2K Blocking Peptide, ubiquitin-conjugating enzyme E2K, UBC1 homolog, yeast Blocking Peptide, DKFZp564C1216 Blocking Peptide, DKFZp686J24237 Blocking Peptide, E2-25K Blocking Peptide, HIP2 Blocking Peptide, HYPG Blocking Peptide, LIG Blocking Peptide, UBE2K, UBEK-2, UBEK 2, UBEK-2 Blocking Peptide, UBEK 2 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
UBE2K
(Ubiquitin-Conjugating Enzyme E2K (UBE2K))
Hintergrund
UBE2K belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation.