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Ubiquitin-Conjugating Enzyme E2K (UBE2K) (Middle Region) Peptid

UBE2K Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN985825
  • Target Alle UBE2K Produkte
    UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 9
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-UBE2K antibody (Catalog #: ARP43049_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))
    Synonyme
    E2-25K Peptide, HIP2 Peptide, HYPG Peptide, LIG Peptide, UBC1 Peptide, E2-25k Peptide, Hip2 Peptide, Hypg Peptide, Lig Peptide, e2-25k Peptide, hip2 Peptide, hypg Peptide, lig Peptide, AW492011 Peptide, D5Ertd601e Peptide, ube2k Peptide, zgc:103472 Peptide, zgc:110791 Peptide, ubiquitin conjugating enzyme E2 K Peptide, ubiquitin-conjugating enzyme E2K Peptide, ubiquitin conjugating enzyme E2 K S homeolog Peptide, ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast) Peptide, ubiquitin-conjugating enzyme E2Ka (UBC1 homolog, yeast) Peptide, UBE2K Peptide, Ube2k Peptide, ube2k.S Peptide, ube2k Peptide, ube2kb Peptide, ube2ka Peptide
    Hintergrund
    UBE2K belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene.

    Alias Symbols: DKFZp564C1216, DKFZp686J24237, E2-25K, HIP2, HYPG, LIG, UBC1

    Protein Interaction Partner: HTT,HTT,NEDD8,NFKB1,PIAS4,TP53,TRIM3,DDX58,DSTYK,HTT,RNF2,UBE2I

    Protein Size: 200
    Molekulargewicht
    22 kDa
    Gen-ID
    3093
    NCBI Accession
    NM_005339, NP_005330
    UniProt
    P61086
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