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Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) Peptid

SF3B1 Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN938085

Kurzübersicht für Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) Peptid (ABIN938085)

Target

SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))

Spezies

Säugetier

Quelle

  • 8
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Protein-Typ

    Synthetic

    Sequenz

    ERLDPFADGG KTPDPKMNAR TYMDVMREQH LTKEEREIRQ QLAEKAKAGE

    Produktmerkmale

    A synthetic peptide for use as a blocking control in assays to test for specificity of SF3 B1 antibody,
    Alternative Names: SF3B1 control peptide, SF3B1 antibody Blocking Peptide, Anti-SF3B1 Blocking Peptide, Splicing Factor 3B Subunit 1 155Kda Blocking Peptide, SF3B1, SFB1-3, SFB1 3, SFB1-3 Blocking Peptide, SFB1 3 Blocking Peptide
  • Applikationshinweise

    Optimal conditions should be determined by the investigator

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20 °C long term.
  • Target

    SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))

    Hintergrund

    SF3B1 is subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures.

    Molekulargewicht

    87 kDa
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