TRAF Family Member-Associated NFKB Activator (TANK) Peptid
TANK
Reaktivität: Säugetier
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN937413
Kurzübersicht für TRAF Family Member-Associated NFKB Activator (TANK) Peptid (ABIN937413)
Target
TANK
(TRAF Family Member-Associated NFKB Activator (TANK))
Spezies
Säugetier
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein-Typ
- Synthetic
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Sequenz
- DKNIGEQLNK AYEAFRQACM DRDSAVKELQ QKTENYEQRI REQQEQLSLQ
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of TANK antibody,
Alternative Names: TANK control peptide, TANK antibody Blocking Peptide, Anti-TANK Blocking Peptide, TRAF family member-associated NFKB activator Blocking Peptide, I-TRAF Blocking Peptide, TRAF2 Blocking Peptide
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- TANK (TRAF Family Member-Associated NFKB Activator (TANK))
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Hintergrund
- The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. TANK is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, TANK can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation.The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily.
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Molekulargewicht
- 48 kDa
Target
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