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TRAF Family Member-Associated NFKB Activator (TANK) (N-Term) Peptid

TANK Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN984763
  • Target Alle TANK Produkte
    TANK (TRAF Family Member-Associated NFKB Activator (TANK))
    Protein Region
    N-Term
    Spezies
    Human
    Quelle
    • 6
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-TANK antibody (Catalog #: ARP38421_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    TANK (TRAF Family Member-Associated NFKB Activator (TANK))
    Synonyme
    I-TRAF Peptide, ITRAF Peptide, TRAF2 Peptide, C86182 Peptide, E430026L09Rik Peptide, zgc:153048 Peptide, i-traf Peptide, tank Peptide, traf2 Peptide, TRAF family member associated NFKB activator Peptide, TRAF family member-associated Nf-kappa B activator Peptide, TRAF family member-associated NFKB activator Peptide, TRAF family member associated NFKB activator L homeolog Peptide, TANK Peptide, Tank Peptide, tank Peptide, tank.L Peptide
    Hintergrund
    The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. TANK is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, TANK can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation.The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Two transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: I-TRAF, TRAF2

    Protein Interaction Partner: CHUK,CHUK,IKBKE,IKBKG,CHUK,IKBKB,IKBKE,IKBKG,MAP4K5,TBK1,TRAF1,TRAF2,TRAF3,USP7,ZC3H12A,CHUK,IKBKE,IKBKG,IRF3,IRF7,ITGB1BP1,TBK1,TRAF1,TRAF2,TRAF3,TRIM37,Tbk1,UBC,ZC3H12A

    Protein Size: 425
    Molekulargewicht
    48 kDa
    Gen-ID
    10010
    NCBI Accession
    NM_004180, NP_004171
    UniProt
    Q92844
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