A synthetic peptide for use as a blocking control in assays to test for specificity of MBD1 antibody, Alternative Names: MBD1 control peptide, MBD1 antibody Blocking Peptide, Anti-MBD1 Blocking Peptide, Methyl-Cpg Binding Domain Protein 1 Blocking Peptide, CXXC3 Blocking Peptide, PCM1 Blocking Peptide, RFT Blocking Peptide, MBD1, MBD-1, MBD 1, MBD-1 Blocking Peptide, MBD 1 Blocking Peptide
MBD1 belongs to a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MBD1 can also repress transcription from methylated gene promoters. Five transcript variants of the MBD1 are generated by alternative splicing resulting in protein isoforms that contain one MBD domain, two to three cysteine-rich (CXXC) domains, and some differences in the COOH terminus.