G protein beta subunit-like (GBL) Peptid
GBL
Reaktivität: Säugetier
Wirt: Synthetic
BP, WB, IHC
Kurzübersicht für G protein beta subunit-like (GBL) Peptid (ABIN937025)
Target
GBL
(G protein beta subunit-like (GBL))
Spezies
Säugetier
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein-Typ
- Synthetic
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Sequenz
- CAFSGDSQYI VTASSDNLAR LWCVETGEIK REYGGHQKAV VCLAFNDSVL
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of GBL antibody,
Alternative Names: GBL control peptide, GBL antibody Blocking Peptide, Anti-GBL Blocking Peptide, Glioblastoma Blocking Peptide, MGC111011 Blocking Peptide
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- GBL (G protein beta subunit-like (GBL))
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Hintergrund
- GBL is the subunit of both mTORC1 and mTORC2, which regulate cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino-acids. Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin.
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Molekulargewicht
- 36 kDa
Target
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