A synthetic peptide for use as a blocking control in assays to test for specificity of PDK1 antibody, Alternative Names: PDK1 control peptide, PDK1 antibody Blocking Peptide, Anti-PDK1 Blocking Peptide, Pyruvate Dehydrogenase Kinase Isozyme 1 Blocking Peptide, PDK1, PDK-1, PDK 1, PDK-1 Blocking Peptide, PDK 1 Blocking Peptide
PDPK1
Reaktivität: Human, Ratte
Wirt: Synthetic
BP, BI
Applikationshinweise
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
PDPK1
(3-phosphoinositide Dependent Protein Kinase-1 (PDPK1))
Synonyme
pdpk1 Peptide, MGC82080 Peptide, PDK1 Peptide, PDPK2 Peptide, PRO0461 Peptide, Pdk1 Peptide, zgc:153787 Peptide, 3'-phosphoinositide-dependent protein kinase 1 Peptide, 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1 Peptide, ATPDK1 Peptide, AtPDK1 Peptide, T32M21.110 Peptide, T32M21_110 Peptide, zgc:77318 Peptide, 3-phosphoinositide dependent protein kinase 1 Peptide, 3-phosphoinositide dependent protein kinase 1 L homeolog Peptide, 3-phosphoinositide dependent protein kinase-1 Peptide, 3-phosphoinositide dependent protein kinase 1a Peptide, 3-phosphoinositide-dependent protein kinase 1 Peptide, 3'-phosphoinositide-dependent protein kinase 1 Peptide, 3-phosphoinositide dependent protein kinase 1b Peptide, PDPK1 Peptide, pdpk1.L Peptide, pdpk1 Peptide, Pdpk1 Peptide, pdpk1a Peptide, LOC100380750 Peptide, pdk-1 Peptide, PDK1 Peptide, pdpk1b Peptide
Hintergrund
Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation.