3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (Middle Region) Peptid
PDPK1
Reaktivität: Maus
Wirt: Synthetic
BP, WB
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- Target Alle PDPK1 Produkte
- PDPK1 (3-phosphoinositide Dependent Protein Kinase-1 (PDPK1))
- Protein Region
- Middle Region
- Spezies
- Maus
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- QYFLDRFYMS RISIRMLLNQ HSLLFGGKGS PSHRKHIGSI NPNCDVVEVI
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- PDK1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) peptide
PDPK1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Hund Wirt: Synthetic BP, Imm
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PDPK1 (3-phosphoinositide Dependent Protein Kinase-1 (PDPK1))
- Synonyme
- pdpk1 Peptide, MGC82080 Peptide, PDK1 Peptide, PDPK2 Peptide, PRO0461 Peptide, Pdk1 Peptide, zgc:153787 Peptide, 3'-phosphoinositide-dependent protein kinase 1 Peptide, 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1 Peptide, ATPDK1 Peptide, AtPDK1 Peptide, T32M21.110 Peptide, T32M21_110 Peptide, zgc:77318 Peptide, 3-phosphoinositide dependent protein kinase 1 Peptide, 3-phosphoinositide dependent protein kinase 1 L homeolog Peptide, 3-phosphoinositide dependent protein kinase-1 Peptide, 3-phosphoinositide dependent protein kinase 1a Peptide, 3-phosphoinositide-dependent protein kinase 1 Peptide, 3'-phosphoinositide-dependent protein kinase 1 Peptide, 3-phosphoinositide dependent protein kinase 1b Peptide, PDPK1 Peptide, pdpk1.L Peptide, pdpk1 Peptide, Pdpk1 Peptide, pdpk1a Peptide, LOC100380750 Peptide, pdk-1 Peptide, PDK1 Peptide, pdpk1b Peptide
- Hintergrund
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Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. Plays an important role in cellular responses to hypoxia and is important for cell proliferation under hypoxia. Protects cells against apoptosis in response to hypoxia and oxidative stress (By similarity).
Alias Symbols: B830012B01, D530020C15Rik
Protein Size: 434 - Gen-ID
- 228026
- NCBI Accession
- NM_172665, NP_766253
- UniProt
- Q8BFP9
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