A synthetic peptide for use as a blocking control in assays to test for specificity of PDK1 antibody, Alternative Names: PDK1 control peptide, PDK1 antibody Blocking Peptide, Anti-PDK1 Blocking Peptide, Pyruvate Dehydrogenase Kinase Isozyme 1 Blocking Peptide, PDK1, PDK-1, PDK 1, PDK-1 Blocking Peptide, PDK 1 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
PDPK1
(3-phosphoinositide Dependent Protein Kinase-1 (PDPK1))
Hintergrund
Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation.