Galanin Receptor 2 (GALR2) Peptid
GALR2
Reaktivität: Säugetier
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN936382
Kurzübersicht für Galanin Receptor 2 (GALR2) Peptid (ABIN936382)
Target
GALR2
(Galanin Receptor 2 (GALR2))
Spezies
Säugetier
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein-Typ
- Synthetic
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Sequenz
- RGTHSGSVLE RESSDLLHMS EAAGALRPCP GASQPCILEP CPGPSWQGPK
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of GALR2 antibody,
Alternative Names: GALR2 control peptide, GALR2 antibody Blocking Peptide, Anti-GALR2 Blocking Peptide, galanin receptor 2 Blocking Peptide, GALNR2 Blocking Peptide, MGC125983 Blocking Peptide, MGC125984 Blocking Peptide, GALR2, GALR-2, GALR 2, GALR-2 Blocking Peptide, GALR 2 Blocking Peptide
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Galanin Receptor 2 (GALR2) peptide
GALR2 Reaktivität: Human, Rind (Kuh), Maus, Hund, Ratte Wirt: Synthetic BP, Imm
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- GALR2 (Galanin Receptor 2 (GALR2))
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Hintergrund
- Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways.
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Molekulargewicht
- 43 kDa
Target
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