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Tribbles Pseudokinase 2 (TRIB2) Peptid

TRIB2 Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN936167

Kurzübersicht für Tribbles Pseudokinase 2 (TRIB2) Peptid (ABIN936167)

Target

TRIB2 (Tribbles Pseudokinase 2 (TRIB2))

Spezies

Säugetier

Quelle

  • 1
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Protein-Typ

    Synthetic

    Sequenz

    YPFHDIEPSS LFSKIRRGQF NIPETLSPKA KCLIRSILRR EPSERLTSQE

    Produktmerkmale

    A synthetic peptide for use as a blocking control in assays to test for specificity of TRIB2 antibody,
    Alternative Names: TRIB2 control peptide, TRIB2 antibody Blocking Peptide, Anti-TRIB2 Blocking Peptide, Tribbles Homolog 2 Blocking Peptide, GS3955 Blocking Peptide, TRB2 Blocking Peptide, TRIB2, TRIB-2, TRIB 2, TRIB-2 Blocking Peptide, TRIB 2 Blocking Peptide
  • Applikationshinweise

    Optimal conditions should be determined by the investigator

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20 °C long term.
  • Target

    TRIB2 (Tribbles Pseudokinase 2 (TRIB2))

    Hintergrund

    TRIB2 is one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia.

    Molekulargewicht

    39 kDa
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