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Tribbles Pseudokinase 2 (TRIB2) (Middle Region) Peptid

TRIB2 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN985471
  • Target Alle TRIB2 Produkte
    TRIB2 (Tribbles Pseudokinase 2 (TRIB2))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 1
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-TRIB2 antibody (Catalog #: ARP55377_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    TRIB2 (Tribbles Pseudokinase 2 (TRIB2))
    Synonyme
    TRIB2 Peptide, Trb2 Peptide, Xtrbl Peptide, gs3955 Peptide, c5fw Peptide, trb2 Peptide, xtrb2 Peptide, TRB2 Peptide, C5FW Peptide, GS3955 Peptide, TRB-2 Peptide, AW319517 Peptide, RGD1564451 Peptide, tribbles pseudokinase 2 Peptide, tribbles pseudokinase 2 S homeolog Peptide, TRIB2 Peptide, trib2 Peptide, trib2.S Peptide, Trib2 Peptide
    Hintergrund
    TRIB2 is one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia.

    Alias Symbols: GS3955, TRB2, C5FW

    Protein Interaction Partner: UBQLN4

    Protein Size: 343
    Molekulargewicht
    39 kDa
    Gen-ID
    28951
    NCBI Accession
    NM_021643, NP_067675
    UniProt
    Q92519
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