Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1) Peptid
LDLRAP1
Reaktivität: Säugetier
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN935977
Kurzübersicht für Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1) Peptid (ABIN935977)
Target
LDLRAP1
(Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1))
Spezies
Säugetier
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
-
-
Protein-Typ
- Synthetic
-
Sequenz
- WTDTRETLLE GMLFSLKYLG MTLVEQPKGE ELSAAAIKRI VATAKASGKK
-
Produktmerkmale
-
A synthetic peptide for use as a blocking control in assays to test for specificity of LDLRAP1 antibody,
Alternative Names: LDLRAP1 control peptide, LDLRAP1 antibody Blocking Peptide, Anti-LDLRAP1 Blocking Peptide, Low Density Lipoprotein Receptor Adaptor Protein 1 Blocking Peptide, ARH Blocking Peptide, ARH1 Blocking Peptide, ARH2 Blocking Peptide, DKFZp586D0624 Blocking Peptide, FHCB1 Blocking Peptide, FHCB2 Blocking Peptide, MGC34705 Blocking Peptide, LDLRAP1, LDLRAP-1, LDLRAP 1, LDLRAP-1 Blocking Peptide, LDLRAP 1 Blocking Peptide
-
-
-
-
Applikationshinweise
- Optimal conditions should be determined by the investigator
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
-
Buffer
- PBS
-
Handhabung
- Avoid repeated freeze/thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20 °C long term.
-
-
- LDLRAP1 (Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1))
-
Hintergrund
- LDLRAP1 is an adapter protein (clathrin-associated sorting protein (CLASP)) required for efficient endocytosis of the LDL receptor (LDLR) in polarized cells such as hepatocytes and lymphocytes, but not in non-polarized cells (fibroblasts). LDLRAP1 may be required for LDL binding and internalization but not for receptor clustering in coated pits. LDLRAP1 may facilitate the endocytocis of LDLR and LDLR-LDL complexes from coated pits by stabilizing the interaction between the receptor and the structural components of the pits.
-
Molekulargewicht
- 34 kDa
Target
-
Sie sind hier:
