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Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1) Peptid

LDLRAP1 Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN935977
  • Target Alle LDLRAP1 Produkte
    LDLRAP1 (Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1))
    Protein-Typ
    Synthetic
    Spezies
    Säugetier
    Quelle
    • 4
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    WTDTRETLLE GMLFSLKYLG MTLVEQPKGE ELSAAAIKRI VATAKASGKK
    Produktmerkmale
    A synthetic peptide for use as a blocking control in assays to test for specificity of LDLRAP1 antibody,
    Alternative Names: LDLRAP1 control peptide, LDLRAP1 antibody Blocking Peptide, Anti-LDLRAP1 Blocking Peptide, Low Density Lipoprotein Receptor Adaptor Protein 1 Blocking Peptide, ARH Blocking Peptide, ARH1 Blocking Peptide, ARH2 Blocking Peptide, DKFZp586D0624 Blocking Peptide, FHCB1 Blocking Peptide, FHCB2 Blocking Peptide, MGC34705 Blocking Peptide, LDLRAP1, LDLRAP-1, LDLRAP 1, LDLRAP-1 Blocking Peptide, LDLRAP 1 Blocking Peptide
  • Applikationshinweise
    Optimal conditions should be determined by the investigator
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C long term.
  • Target
    LDLRAP1 (Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1))
    Hintergrund
    LDLRAP1 is an adapter protein (clathrin-associated sorting protein (CLASP)) required for efficient endocytosis of the LDL receptor (LDLR) in polarized cells such as hepatocytes and lymphocytes, but not in non-polarized cells (fibroblasts). LDLRAP1 may be required for LDL binding and internalization but not for receptor clustering in coated pits. LDLRAP1 may facilitate the endocytocis of LDLR and LDLR-LDL complexes from coated pits by stabilizing the interaction between the receptor and the structural components of the pits.
    Molekulargewicht
    34 kDa
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