Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (C-Term) Peptid
Kurzübersicht für Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (C-Term) Peptid (ABIN8110592)
Target
Spezies
Quelle
Applikation
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Protein Region
- C-Term
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Verwendungszweck
- RRM2B Peptide - C-terminal region
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Sequenz
- IEFVADRLLV ELGFSKVFQA ENPFDFMENI SLEGKTNFFE KRVSEYQRFA
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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This is a synthetic peptide designed for use in combination with anti- RRM2B Antibody (ARP87556_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
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Hintergrund
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Background Information: This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.
Alternative Symbols: P53R2, MTDPS8A, MTDPS8B
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Molekulargewicht
- 32 kDa
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Gen-ID
- 50484
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NCBI Accession
- NP_001165948
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UniProt
- Q7LG56
Target
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