Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (C-Term) Peptid
RRM2B
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle RRM2B Produkte
- RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
- Protein Region
- C-Term
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- IEFVADRLLV ELGFSKVFQA ENPFDFMENI SLEGKTNFFE KRVSEYQRFA
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- RRM2B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
- Synonyme
- p53r2 Peptide, RRM2B Peptide, MTDPS8A Peptide, MTDPS8B Peptide, P53R2 Peptide, p53R2 Peptide, ribonucleotide reductase M2 B (TP53 inducible) S homeolog Peptide, ribonucleotide reductase regulatory TP53 inducible subunit M2B Peptide, ribonucleotide reductase M2 B (TP53 inducible) Peptide, rrm2b.S Peptide, RRM2B Peptide, rrm2b Peptide, Rrm2b Peptide
- Hintergrund
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This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.
Alias Symbols: P53R2, MTDPS8A, MTDPS8B
Protein Size: 299 - Gen-ID
- 50484
- NCBI Accession
- NM_001172477, NP_001165948
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