Paired-Like Homeobox 2a (PHOX2A) (C-Term) Peptid
Kurzübersicht für Paired-Like Homeobox 2a (PHOX2A) (C-Term) Peptid (ABIN8107574)
Target
Spezies
Quelle
Applikation
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Protein Region
- C-Term
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Verwendungszweck
- PHOX2A Peptide - C-terminal region
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Sequenz
- VAGGGGGGPG AGAAELLKAW QPAESGPGPF SGVLSSFHRK PGPALKTNLF
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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This is a synthetic peptide designed for use in combination with anti-PHOX2A Antibody (ARP38570_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- PHOX2A (Paired-Like Homeobox 2a (PHOX2A))
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Hintergrund
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Background Information: PHOX2A contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. PHOX2A has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene.
Alternative Symbols: ARIX, CFEOM2, FEOM2, MGC52227, NCAM2, PMX2A
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Molekulargewicht
- 30kDa
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Gen-ID
- 401
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NCBI Accession
- NP_005160
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UniProt
- O14813
Target
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