High Mobility Group AT-Hook 1 (HMGA1) (N-Term) Peptid
Kurzübersicht für High Mobility Group AT-Hook 1 (HMGA1) (N-Term) Peptid (ABIN8102506)
Target
Spezies
Quelle
Applikation
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Protein Region
- N-Term
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Verwendungszweck
- HMGA1 Peptide - N-terminal region
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Sequenz
- QPLASKQEKD GTEKRGRGRP RKQPPVSPGT ALVGSQKEPS EVPTPKRPRG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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This is a synthetic peptide designed for use in combination with anti-HMGA1 Antibody (ARP73988_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))
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Hintergrund
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Background Information: This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene.
Alternative Symbols: HMGA1,HMGIY,
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Molekulargewicht
- 11kDa
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Gen-ID
- 3159
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NCBI Accession
- XP_005249118
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UniProt
- P17096
Target
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