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Chromobox Homolog 7 (CBX7) Peptid

CBX7 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN8097013
168,15 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 6 bis 9 Werktagen

Kurzübersicht für Chromobox Homolog 7 (CBX7) Peptid (ABIN8097013)

Target

CBX7 (Chromobox Homolog 7 (CBX7))

Spezies

Human

Quelle

  • 5
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Verwendungszweck

    CBX7 Peptide
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Kommentare

    This is a synthetic peptide designed for use in combination with anti-CBX7 antibody ( ARP74429_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Buffer

    Lyophilized powder

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
  • Target

    CBX7 (Chromobox Homolog 7 (CBX7))

    Hintergrund

    CBX7 is a component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.

    Molekulargewicht

    27

    Gen-ID

    23492

    NCBI Accession

    NP_783640

    UniProt

    O95931
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