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Chromobox Homolog 7 (CBX7) Peptid

CBX7 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5512656
  • Target Alle CBX7 Produkte
    CBX7 (Chromobox Homolog 7 (CBX7))
    Spezies
    Human
    Quelle
    • 3
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-CBX7 antibody (Catalog #: ARP74429_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    CBX7 (Chromobox Homolog 7 (CBX7))
    Synonyme
    1600014J01Rik Peptide, AI851678 Peptide, D15Ertd417e Peptide, zgc:110152 Peptide, chromobox 7 Peptide, chromobox homolog 7a Peptide, CBX7 Peptide, Cbx7 Peptide, cbx7a Peptide
    Hintergrund
    CBX7 is a component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.

    Protein Size: 251
    Molekulargewicht
    27 kDa
    Gen-ID
    23492
    NCBI Accession
    NP_783640
    UniProt
    O95931
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