Minichromosome Maintenance Complex Component 3 (MCM3) (Middle Region) Peptid
MCM3
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN5673396
Kurzübersicht für Minichromosome Maintenance Complex Component 3 (MCM3) (Middle Region) Peptid (ABIN5673396)
Target
MCM3
(Minichromosome Maintenance Complex Component 3 (MCM3))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- RRYSDLTTLV AFPSSSVYPT KDEENNPLET EYGLSVYKDH QTITIQEMPE
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- MCM3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))
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Hintergrund
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The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: HCC5, P1.h, RLFB, P1-MCM3
Protein Size: 853 -
Gen-ID
- 4172
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NCBI Accession
- NM_001270472, NP_001257401
Target
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